What is Actos?

You've no doubt come to Actoslawsuit.com because you have type 2 diabetes and are troubled by the Food and Drug Administration announcement that your medicines containing Actos, or pioglitazone, may have a potential bladder cancer risk.

We Have the Actos Information You Need!

Wading through scientific reports is daunting. Our goal is provide patients and their families with the important informatino they need.

On the following pages you'll learn about type 2 diabetes and how it's controlled. You'll also discover how Actos works, learn about its side effects and find out the ongoing concerns about it.


Type 2 Diabetes Medications Work to Reduce Blood Sugar

Type 2 diabetes is a disease that affects how your body uses sugar for fuel. This disease currently affects about 18.8 million Americans.

Normally your digestive system converts food into sugar and sends it to your bloodstream to be absorbed by the cells in your muscles and fat to keep you moving. Unused sugar is stored in your liver for release whenever you're short of energy. But whether the sugar comes from food or your liver, it can't get inside your cells without an escort, the hormone insulin, made by your pancreas.

But type 2 diabetics either can't make enough insulin, or their cells aren't as sensitive to it as they should be, so sugar builds up in their blood, leaving them tired. What's more, high blood sugar can cause heart attacks, strokes, circulation problems, kidney damage and blindness.

So, doctors prescribe medicines to help, and there are many of them on the market today.

The Agency for Healthcare Research and Quality reports that there are 11 classes of type 2 diabetes drugs, with several drugs within each class. From 2005 to 2006, 35 percent of the patients taking medication took drugs from two classes and another 14 percent took drugs from three or more classes.

These drugs work by doing one or more of the following:

  • Stimulating the pancreas to make more insulin
  • Reducing the amount of sugar stored and released by the liver
  • Blocking stomach enzymes from breaking down sugar in starchy food
  • Sensitizing cells to insulin

How Does Actos Work?

Actos, also known by its chemical or generic name – pioglitazone – controls your blood sugar by helping your body's cells become more sensitive to existing insulin. In addition, Actos decreases the amount of sugar your liver releases into the bloodstream.

Actos can be prescribed alone, or in combination with other diabetes drugs. The combination drugs are known by the following names:

  • Actoplus Met (pioglitazone/metformin)
  • Actoplus Met XR (pioglitazone/metformin extended release)
  • Duetact (pioglitazone/glimepride)
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